CAS RN 1629268-00-3
CAS RN 1629268-00-3
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ARS-853, MedChemExpress
MedChemExpress ARS-853 is a cell-active, selective, covalent KRAS G12C inhibitor with an IC50 of 2.5 μM. ARS-853 inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation.