CAS RN 1380424-42-9
CAS RN 1380424-42-9
IUPAC Name:
1,1,1,3,3,3-hexafluoropropan-2-yl 4-[bis(2H-1,3-benzodioxol-5-yl)(hydroxy)methyl]piperidine-1-carboxylate
Synonyms:
1,1,1,3,3,3-hexafluoropropan-2-yl 4-[bis(2H-1,3-benzodioxol-5-yl)(hydroxy)methyl]piperidine-1-carboxylate
Molecular Weight (g/mol):
549.42
Molecular Formula:
C24H21F6NO7
InChi Key:
SXHQLPHDBLTFPM-UHFFFAOYSA-N
SMILES:
OC(C1CCN(CC1)C(=O)OC(C(F)(F)F)C(F)(F)F)(C1=CC2=C(OCO2)C=C1)C1=CC2=C(OCO2)C=C1
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Tocris Bioscience™ KML 29
CAS: 1380424-42-9 Molecular Formula: C24H21F6NO7
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KML29, MedChemExpress
MedChemExpress KML29 is an extremely selective, orally active and irreversible MAGL inhibitor, with IC50 values of 15 nM, 43 nM and 5.9 nM for mouse, rat and human MAGL, respectively. KML29 exhibits minimal cross-reactivity toward other central and peripheral serine hydrolases, including no detectable activity against FAAH.
