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KML29, MedChemExpress

Product Code. p-200097979
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Quantity:
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Product Code. 16487668

Brand: Medchem Express HY18977

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Description

MedChemExpress KML29 is an extremely selective, orally active and irreversible MAGL inhibitor, with IC50 values of 15 nM, 43 nM and 5.9 nM for mouse, rat and human MAGL, respectively. KML29 exhibits minimal cross-reactivity toward other central and peripheral serine hydrolases, including no detectable activity against FAAH.

KML29 is an extremely selective, orally active and irreversible MAGL inhibitor, with IC50 values of 15 nM, 43 nM and 5.9 nM for mouse, rat and human MAGL, respectively. KML29 exhibits minimal cross-reactivity toward other central and peripheral serine hydrolases, including no detectable activity against FAAH.

Specifications

Chemical Name or Material KML29
CAS 1380424-42-9
Color White
Purity Grade Notes Research
Molecular Formula C24H21F6NO7
Quantity 10 mg
Solubility Information DMSO : 50 mg/mL (91.01 mM; Need ultrasonic)
SMILES O=C(N1CCC(C(C2=CC=C(OCO3)C3=C2)(C4=CC=C(OCO5)C5=C4)O)CC1)OC(C(F)(F)F)C(F)(F)F
Molecular Weight (g/mol) 549.42
Formula Weight 549.42
Percent Purity 98.77%
Grade Research
Physical Form Solid
For Use With (Application) Metabolism-sugar/lipid metabolism
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Research purposes only

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