CAS RN 134308-13-7
CAS RN 134308-13-7
IUPAC Name:
5-(4-methylbenzoyl)-3-nitrobenzene-1,2-diol
Synonyms:
tolcapone tasmar
Molecular Weight (g/mol):
273.24
Molecular Formula:
C14H11NO5
InChi Key:
MIQPIUSUKVNLNT-UHFFFAOYSA-N
SMILES:
CC1=CC=C(C=C1)C(=O)C1=CC(O)=C(O)C(=C1)[N+]([O-])=O
1
–
5
of
5
results
1
Thermo Scientific Chemicals Tolcapone
CAS: 134308-13-7 Molecular Formula: C14H11NO5 Molecular Weight (g/mol): 273.24 InChI Key: MIQPIUSUKVNLNT-UHFFFAOYSA-N IUPAC Name: 5-(4-methylbenzoyl)-3-nitrobenzene-1,2-diol SMILES: CC1=CC=C(C=C1)C(=O)C1=CC(O)=C(O)C(=C1)[N+]([O-])=O
2
Tocris Bioscience™ Tolcapone
COMT inhibitor; also inhibits transthyretin aggregation
3
Tolcapone, MedChemExpress
MedChemExpress Tolcapone (Ro 40-7592) is a selective, orally active and powerful mixed (peripheral and central) COMT inhibitor with an IC50 of 773 nM in the liver. Tolcapone is also a potent inhibitor of α-syn and Aβ42 oligomerization and fibrillogenesis. Tolcapone induces oxidative stress leading to apoptosis and inhibition of tumor growth in neuroblastoma.
4
5