CAS RN 1320346-97-1

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Potent αv integrin inhibitor

Target	Integrin Receptor Inhibitors
CAS	1320346-97-1
Purity	0.97
Chemical Name or Material	3-[[2,5-Dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)sulfonyl]-L-alanine
Recommended Storage	Store at -20°C
Molecular Formula	C₂₉H₃₇N₇O₅S

MedChemExpress GLPG0187 is a broad spectrum integrin receptor antagonist with antitumor activity; inhibits αvβ1-integrin with an IC50 of 1.3 nM.

Molecular Weight (g/mol)	595.71
Color	White
Physical Form	Solid
Chemical Name or Material	GLPG0187
Grade	Research
SMILES	O=C(O)[C@H](CNC1=NC(C)=NC(N2CCC(C3=NC4=C(CCCN4)C=C3)CC2)=C1C)NS(=O)(C5=CC=C(OC)C=C5)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.95%
CAS	1320346-97-1
Solubility Information	DMSO : 12.5 mg/mL (20.98 mM; ultrasonic and warming and heat to 60°C) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₉H₃₇N₇O₅S
Formula Weight	595.71