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CAS RN 1140909-48-3

H3CONOH3CONHOOHNFOOHOHOOH

CAS RN 1140909-48-3

IUPAC Name: 2-hydroxybutanedioic acid; N'1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Synonyms: cabozantinib; malic acid
Molecular Weight (g/mol): 635.6
Molecular Formula: C32H30FN3O10
InChi Key: HFCFMRYTXDINDK-UHFFFAOYNA-N
SMILES: OC(CC(O)=O)C(O)=O.COC1=C(OC)C=C2C(OC3=CC=C(NC(=O)C4(CC4)C(=O)NC4=CC=C(F)C=C4)C=C3)=CC=NC2=C1
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1 – 4 of 4 results
1

Cabozantinib (S)-malate, Thermo Scientific™

CAS: 1140909-48-3 Molecular Formula: C32H30FN3O10 Molecular Weight (g/mol): 635.60 MDL Number: MFCD20923480 InChI Key: HFCFMRYTXDINDK-UHFFFAOYNA-N IUPAC Name: 2-hydroxybutanedioic acid; N'1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide SMILES: OC(CC(O)=O)C(O)=O.COC1=C(OC)C=C2C(OC3=CC=C(NC(=O)C4(CC4)C(=O)NC4=CC=C(F)C=C4)C=C3)=CC=NC2=C1

CAS 1140909-48-3
Molecular Weight (g/mol) 635.60
MDL Number MFCD20923480
SMILES OC(CC(O)=O)C(O)=O.COC1=C(OC)C=C2C(OC3=CC=C(NC(=O)C4(CC4)C(=O)NC4=CC=C(F)C=C4)C=C3)=CC=NC2=C1
IUPAC Name 2-hydroxybutanedioic acid; N'1-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N1-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
InChI Key HFCFMRYTXDINDK-UHFFFAOYNA-N
Molecular Formula C32H30FN3O10
2

Cabozantinib (S)-Malate, Mikromol™

Discover Mikromol - your trusted source for high-quality pharmaceutical reference standards. Supporting accurate, compliant analysis with ISO 17034-accredited materials designed for confidence in every result.

3

Cabozantinib L-Malate Salt, TRC

CAS: 1140909-48-3 Molecular Formula: C28 H24 F N3 O5 . C4 H6 O5 Molecular Weight (g/mol): 635.59 Synonym: Butanedioic acid, 2-hydroxy-, (2S)-, compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1),Cabozantinib S-malate,Cabozantinib s-malate,Cometriq,XL 184,Cabozantinib L-malate salt,Cabozantinib (S)-malate IUPAC Name: 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid SMILES: COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc5ccc(F)cc5)cc3)c2cc1OC.O[C@@H](CC(=O)O)C(=O)O

CAS 1140909-48-3
Molecular Weight (g/mol) 635.59
SMILES COc1cc2nccc(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc5ccc(F)cc5)cc3)c2cc1OC.O[C@@H](CC(=O)O)C(=O)O
Synonym Butanedioic acid, 2-hydroxy-, (2S)-, compd. with N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1),Cabozantinib S-malate,Cabozantinib s-malate,Cometriq,XL 184,Cabozantinib L-malate salt,Cabozantinib (S)-malate
IUPAC Name 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide;(2S)-2-hydroxybutanedioic acid
Molecular Formula C28 H24 F N3 O5 . C4 H6 O5
4

Cabozantinib S-malate, MedChemExpress

MedChemExpress Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 635.59
Color White
Physical Form Solid
Chemical Name or Material Cabozantinib S-malate
Grade Research
SMILES O=C([C@H](CC(O)=O)O)O.O=C(NC1=CC=C(C=C1)OC2=CC=NC3=CC(OC)=C(C=C23)OC)C4(CC4)C(NC5=CC=C(C=C5)F)=O
For Use With (Application) Cancer-Kinase/protease
Percent Purity 99.29%
CAS 1140909-48-3
Solubility Information DMSO : ≥ 23 mg/mL (36.19 mM) ∣H2O : < 0.1 mg/mL (insoluble)
Synonym XL184 S-malateBMS-907351 S-malate
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C32H30FN3O10
Formula Weight 635.59