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  8. Cabozantinib S-malate, MedChemExpress

Cabozantinib S-malate, MedChemExpress

Product Code. 16481026
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Product Code. 16481026 Supplier Medchem Express Supplier No. HY12044

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Description

MedChemExpress Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.

Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.

Specifications

Chemical Name or Material Cabozantinib S-malate
CAS 1140909-48-3
Color White
Purity Grade Notes Research
Molecular Formula C32H30FN3O10
Quantity 200 mg
Synonym XL184 S-malateBMS-907351 S-malate
Solubility Information DMSO : ≥ 23 mg/mL (36.19 mM) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C([C@H](CC(O)=O)O)O.O=C(NC1=CC=C(C=C1)OC2=CC=NC3=CC(OC)=C(C=C23)OC)C4(CC4)C(NC5=CC=C(C=C5)F)=O
Molecular Weight (g/mol) 635.59
Formula Weight 635.59
Percent Purity 99.29%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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