| Content And Storage |
-20°C, Avoid Freeze/Thaw Cycles |
| Purity or Quality Grade |
>95% as determined by SDS-PAGE. |
| Conjugate |
Unconjugated |
| Form |
Lyophilized |
| Common Name |
Nectin 2 |
| Molecular Weight (g/mol) |
70-80 kDa |
| Gene Symbol |
NECTIN2 |
| Activity |
1. Measured by its binding ability in a functional ELISA. Immobilized human CD226 (at 2 μg/ml (100 μL/well) can bind human CD112 with a linear range of 6.4-800 ng/mL 2. Immobilized PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His Tag) (at 2 μg/ml (100 μL/well) can bind Nectin-2 Protein, Human, Recombinant (hFc Tag), the EC50 of Nectin-2 Protein, Human, Recombinant (hFc Tag)is 0.2-1.2 ng/mL)) |
| Endotoxin Concentration |
<1.0 EU/μg |
| Sequence |
Human CD112, amino acids Met1-Leu360 (Accession # NP_002847.1) with a C-terminal human IgG1 Fc region |
| Expression System |
HEK293 cells |
| For Use With (Application) |
ELISA |
| Name |
Human Nectin-2 (CD112) Fc Chimera |
| Accession Number |
Q92692 |
| Regulatory Status |
RUO |
| Purification Method |
SDS-PAGE |
| Gene Alias |
AI325026; AI987993; CD112; herpes virus entry mediator B; Herpesvirus entry mediator B; herpesvirus entry protein B; hveB; mHveB; MPH; Murine herpes virus entry protein B; murine herpesvirus entry protein B; nectin cell adhesion molecule 2; Nectin2; Nectin-2; Poliovirus receptor homolog; poliovirus receptor related 2; poliovirus receptor-like 2; poliovirus receptor-related 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); poliovirus receptor-related protein 2; poliovirus sensitivity; PRR2; Pvr; Pvrl2; PVRR2; Pvs |
| Format |
Lyophilized |
| Product Type |
Protein |
| Biological Activity |
1. Measured by its binding ability in a functional ELISA. Immobilized human CD226 at 2 μg/ml (100 μL/well) can bind human CD112 with a linear range of 6.4-800 ng/mL 2. Immobilized PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His Tag) (at 2 μg/ml (100 μL/well) can bind Nectin-2 Protein, Human, Recombinant (hFc Tag), the EC50 of Nectin-2 Protein, Human, Recombinant (hFc Tag)is 0.2-1.2 ng/mL) |
| Gene ID (Entrez) |
5819 |
| Formulation |
50 mM tris with <0.1 μg/mL BSA, 0.01% mannitol, 0.01% Tween 80, 100 mM glycine, 10 mM NaCl, 5-8% trehalose and no preservative; pH 7.5 |
| Protein Tag |
Fc-tag |
| Recombinant |
Recombinant |