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Tocris Bioscience™ TDZD 8
Selective non-ATP competitive inhibitor of GSK 3β
Brand: Tocris Bioscience™ 6092/50
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Description
TDZD 8 is a selective non-ATP competitive inhibitor of GSK 3β (IC50 = 2 μM); thiadiazolidinone deriviative. Does not inhibit Cdk-1/cyclin B, CK-II, PKA or PKC at >100 μM. Reduces severity of L-dopa-induced dyskinesia in a Parkinson's disease in vivo model.Specifications
| White | |
| 327036-89-5 | |
| 222.26g/mol | |
| Soluble to 100mM in DMSO, 100mM in ethanol | |
| Inhibits GSK 3β |
| Inhibitor | |
| C10H10N2O2S | |
| NP 01139 | |
| Store at -20°C | |
| 50 mg |
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