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SKI II, MedChemExpress

Product Code. 16493386
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Product Code. 16493386 Supplier Medchem Express Supplier No. HY13822

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Description

MedChemExpress SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation.

SKI-II is an oral active and synthetic inhibitor of sphingosine kinase (SK) activity, with IC50 values of 78 μM and 45 μM for SK1 and for SK2, respectively. SKI II causes an irreversible inhibition of SK1 by inducing its lysosomal and/or proteasomal degradation.

Specifications

Chemical Name or Material SKI II
CAS 312636-16-1
Color White
Purity Grade Notes Research
Molecular Formula C15H11ClN2OS
Quantity 25 mg
Solubility Information DMSO : ≥ 100 mg/mL (330.27 mM)
SMILES OC1=CC=C(NC2=NC(C3=CC=C(Cl)C=C3)=CS2)C=C1
Molecular Weight (g/mol) 302.78
Formula Weight 302.78
Percent Purity 99.88%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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