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  5. Tocris Bioscience™ AMN 082 dihydrochloride

Tocris Bioscience™ AMN 082 dihydrochloride
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Product Code. 18085492
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Product Code. 18085492 Supplier Tocris Bioscience™ Supplier No. 2385/10

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Description

Selective mGlu7 agonist

AMN 082 dihydrochloride is a the first selective mGlu7 agonist. Potently inhibits cAMP accumulation and stimulates GTPγS binding in recombinant cells and on membranes expressing mGlu7 (EC50 = 64 - 290 nM). Selective over other mGluR subtypes and selected ionotropic glutamate receptors up to 10 μM. Acts via a novel allosteric site and is orally active and brain penetrant. Reduces haloperidol-induced catalepsy in rats.

View important information regarding the usage of AMN 082 dihydrochloride .

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Chemical Identifiers

CAS 97075-46-2
Molecular Formula C28H30Cl2N2

Specifications

Quantity 10 mg
Formula Weight 465.45
Purity >99%
Molecular Weight (g/mol) 465.462
Chemical Name or Material AMN 082 dihydrochloride
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