CAS RN 2074607-48-8

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IWP-O1, MedChemExpress

MedChemExpress IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.

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Specifications

Molecular Weight (g/mol)	432.48
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	IWP-O1
Grade	Research
SMILES	O=C(CN1N=NC(C2=CC=NC=C2)=C1C3=CC=CC=C3)NC4=NC=C(C5=CC=CC=C5)C=C4
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.61%
CAS	2074607-48-8
Solubility Information	DMSO : 125 mg/mL (289.03 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Shelf Life	4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molecular Formula	C₂₆H₂₀N₆O
Formula Weight	432.48

CAS RN 2074607-48-8

CAS RN 2074607-48-8

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