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IWP-O1, MedChemExpress

Product Code. p-200096787
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16425927 5 mg 5mg
16424476 100 mg 100mg
16412666 25 mg 25mg
16409746 50 mg 50mg
16403198 10 mg 10mg
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Product Code. 16425927 Supplier Medchem Express Supplier No. HY100853

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Description

MedChemExpress IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.

IWP-O1 is a highly potent Porcupine (Porcn) inhibitor, with an EC50 of 80 pM in L-Wnt-STF cells. IWP-O1 prevents the secretion of Wnt proteins. IWP-O1 suppresses the phosphorylation of Dvl2/3 and LRP6 in HeLa cells.

Specifications

Chemical Name or Material IWP-O1
CAS 2074607-48-8
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C26H20N6O
Quantity 5 mg
Solubility Information DMSO : 125 mg/mL (289.03 mM; Need ultrasonic)
SMILES O=C(CN1N=NC(C2=CC=NC=C2)=C1C3=CC=CC=C3)NC4=NC=C(C5=CC=CC=C5)C=C4
Molecular Weight (g/mol) 432.48
Formula Weight 432.48
Percent Purity 99.61%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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