CAS RN 186497-07-4

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Zibotentan, MedChemExpress

MedChemExpress Zibotentan (ZD4054) is a potent, selective and orally active endothelin A (ETA) receptor antagonist with a Ki of 13 nM. Zibotentan has no inhibitory effect on ETB. Zibotentan has anticancer effects and can be used for castration-resistant prostate cancer (CRPC) research.

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Specifications

Molecular Weight (g/mol)	424.43
Color	White
Physical Form	Solid
Chemical Name or Material	Zibotentan
Grade	Research
SMILES	O=S(NC1=NC=C(C)N=C1OC)(C2=CC=CN=C2C3=CC=C(C4=NN=CO4)C=C3)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.19%
CAS	186497-07-4
Solubility Information	DMSO : 25 mg/mL (58.90 mM; Need ultrasonic)
Health Hazard 1	H302
Synonym	ZD4054
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₁₆N₆O₄S
Formula Weight	424.43

CAS RN 186497-07-4

CAS RN 186497-07-4

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