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CAS RN 104987-11-3

H2OCH3O(R)(R)OHCH3(S)OO(S)NOO(R)OHO(R)(S)(S)H3C(R)CH2O(S)OH(R)CH3CH3OCH3(S)(R)CH3OCH3(E)(E)

CAS RN 104987-11-3

IUPAC Name: (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo[22.3.1.0⁴,⁹]octacos-18-ene-2,3,10,16-tetrone hydrate
Synonyms: tacrolimus
Molecular Weight (g/mol): 822.05
Molecular Formula: C44H71NO13
InChi Key: NWJQLQGQZSIBAF-HZXKVGIDSA-N
SMILES: O.CO[C@@H]1CC(CC[C@H]1O)\C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)C\C(C)=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC
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1 – 4 of 4 results
1

Thermo Scientific™ Tacrolimus, 99+%

Assay: ≥99% CAS: 104987-11-3 Formula Weight: 804.02g/mol Synonym: FK-506; Fugimycin Content And Storage: -30°C to -10°C Format: Powder For Use With (Application): Interacts with the immunophilins cyclophilin and FKBP-12 Description: White to Off-white Melting Point: 120°C to 125°C Solubility: Freely soluble in DMSO or ethanol; Poorly soluble in water

Assay ≥99%
Content And Storage -30°C to -10°C
Description White to Off-white
Format Powder
CAS 104987-11-3
Solubility Freely soluble in DMSO or ethanol; Poorly soluble in water
Synonym FK-506; Fugimycin
For Use With (Application) Interacts with the immunophilins cyclophilin and FKBP-12
Formula Weight 804.02g/mol
Melting Point 120°C to 125°C
2

Tacrolimus (FK506), TRC

CAS: 104987-11-3 Molecular Formula: C44 H69 N O12 Molecular Weight (g/mol): 804.02 SMILES: CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)\[C@H]2OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@]4(O)O[C@H]([C@H](C[C@@H](C)C\C(=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)\C)OC)[C@H](C[C@H]4C)OC

CAS 104987-11-3
Molecular Weight (g/mol) 804.02
SMILES CO[C@@H]1C[C@@H](CC[C@H]1O)\C=C(/C)\[C@H]2OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@]4(O)O[C@H]([C@H](C[C@@H](C)C\C(=C\[C@@H](CC=C)C(=O)C[C@H](O)[C@H]2C)\C)OC)[C@H](C[C@H]4C)OC
Molecular Formula C44 H69 N O12
3

STEMCELL Technologies FK506

Calcineurin/NFAT pathway inhibitor; Binds FKBP-12

ENCOMPASS_PREFERRED
CAS 104987-11-3
Purity ≥99%
Synonym Tacrolimus
Molecular Formula C44H69NO12
4

Tacrolimus, MedChemExpress

MedChemExpress Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 804.02
Color White
Physical Form Powder
Chemical Name or Material Tacrolimus
Grade Research
SMILES O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@H](OC)[C@@](O2)([H])[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC=C)=O)=O)O[C@H](/C(C)=C/[C@H]4C[C@@H](OC)[C@H](O)CC4)[C@H](C)[C@@H](O)CC3=O
For Use With (Application) COVID-19-immunoregulation
Percent Purity 95.2%
CAS 104987-11-3
Solubility Information DMSO : ≥ 150 mg/mL (186.56 mM)
Synonym FK506 Fujimycin FR900506
Purity Grade Notes Research
Recommended Storage 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Shelf Life 4°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light)
Molecular Formula C44H69NO12
Formula Weight 804.02