Benzenesulfonamides
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Filtered Search Results
AKR1C3-IN-1, MedChemExpress
MedChemExpress AKR1C3-IN-1 is a potent, highly selective inhibitor of AKR1C3, with an IC50 of 13 nM.
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| Molecular Weight (g/mol) | 317.36 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | AKR1C3-IN-1 |
| Grade | Research |
| SMILES | O=S(N1CC2=CC=CC=C2CC1)(C3=CC(C(O)=O)=CC=C3)=O |
| Percent Purity | 98.74% |
| CAS | 327092-81-9 |
| Solubility Information | DMSO : ≥ 100 mg/mL (315.10 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H15NO4S |
| Formula Weight | 317.36 |
FASN-IN-4, MedChemExpress
MedChemExpress FASN-IN-4 is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 also inhibits SARS-CoV-2 with an EC50 of 18.6 nM.
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NXT629, MedChemExpress
MedChemExpress NXT629 is a potent, selective, and competitive PPAR-α antagonist, with an IC50 of 77 nM for human PPARα, shows high selectivity over other nuclear hormone receptor, such as PPARδ, PPARγ, ERβ, GR and TRβ, IC50s are 6.0, 15, 15.2, 32.5 and >100 μM, respectively. NXT629 has potent anti-tumor activity and inhibits experimental metastasis of cancer cell in animal models.
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| Molecular Weight (g/mol) | 609.78 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | NXT629 |
| Grade | Research |
| SMILES | O=S(C1=CC=CC=C1)(NC2=CC=C(C3=CC=C(CCCC(N4CC)=NN(CC5=CC=C(C(C)(C)C)C=C5)C4=O)C=C3)N=C2)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 99.2% |
| CAS | 1454925-59-7 |
| Solubility Information | DMSO : 125 mg/mL (204.99 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C35H39N5O3S |
| Formula Weight | 609.78 |
Pazopanib, MedChemExpress
MedChemExpress Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.
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| Molecular Weight (g/mol) | 437.52 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Pazopanib |
| Grade | Research |
| SMILES | O=S(C1=CC(NC2=NC=CC(N(C3=CC4=NN(C(C)=C4C=C3)C)C)=N2)=CC=C1C)(N)=O |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.0% |
| CAS | 444731-52-6 |
| Solubility Information | DMSO : 62.5 mg/mL (142.85 mM; Need ultrasonic) |
| Synonym | GW786034 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C21H23N7O2S |
| Formula Weight | 437.52 |
Sulfachloropyridazine, MedChemExpress
MedChemExpress Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria.
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S0859, MedChemExpress
MedChemExpress S0859 is a selective, high-affinity generic Na+/HCO3- transporter (NBC) inhibitor. S0859 reversibly inhibits NBC-mediated intracellular pH (pHi) recovery (Ki=1.7 μM, full inhibition at approximately 30 μM).
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| Molecular Weight (g/mol) | 530.04 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | S0859 |
| Grade | Research |
| SMILES | O=C(N(CC1=CC=C(C2=CC=CC=C2S(=O)(NC#N)=O)C=C1)CC3=CC=C(C)C=C3)C4=CC=CC=C4Cl |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 98.0% |
| CAS | 1019331-10-2 |
| Solubility Information | DMSO : ≥ 100 mg/mL (188.67 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C29H24ClN3O3S |
| Formula Weight | 530.04 |
Sulfacarbamide, MedChemExpress
MedChemExpress Sulfacarbamide is a blood sugar-lowering drug, also acting on the vegetative nervous system.
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2-Aminobenzenesulfonamide, MedChemExpress
MedChemExpress 2-Aminobenzenesulfonamide is a carbonic anhydrase IX inhibitor.
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KI696, MedChemExpress
MedChemExpress KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction.
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| Molecular Weight (g/mol) | 550.63 |
|---|---|
| Color | Off-White |
| Physical Form | Solid |
| Chemical Name or Material | KI696 |
| Grade | Research |
| SMILES | COC1=C(N2C)C(N=N2)=CC([C@H](C3=CC(CN(C[C@H]4C)S(=O)(C5=CC=CC=C5O4)=O)=C(C)C=C3)CC(O)=O)=C1 |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 98.0% |
| CAS | 1799974-70-1 |
| Solubility Information | DMSO : 50 mg/mL (90.81 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C28H30N4O6S |
| Formula Weight | 550.63 |
VR23, MedChemExpress
MedChemExpress VR23 is a small molecule that potently inhibits the activities of trypsin-like proteasomes (IC50=1 nM), chymotrypsin-like proteasomes (IC50=50-100 nM), and caspase-like proteasomes (IC50=3 μM).
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| Molecular Weight (g/mol) | 477.88 |
|---|---|
| Color | Yellow |
| Physical Form | Solid |
| Chemical Name or Material | VR23 |
| Grade | Research |
| SMILES | O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C23)CC1)(C4=CC=C([N+]([O-])=O)C=C4[N+]([O-])=O)=O |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.05% |
| CAS | 1624602-30-7 |
| Solubility Information | DMSO : 33.33 mg/mL (69.75 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H16ClN5O6S |
| Formula Weight | 477.88 |
ISCK03, MedChemExpress
MedChemExpress ISCK03 is a specific SCF/c-Kit inhibitor.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 355.45 |
|---|---|
| Color | Light Yellow |
| Physical Form | Powder |
| Chemical Name or Material | ISCK03 |
| Grade | Research |
| SMILES | O=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=CC=C(N3C=CN=C3)C=C2)=O |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 99.27% |
| CAS | 945526-43-2 |
| Solubility Information | DMSO : ≥ 38 mg/mL (106.91 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H21N3O2S |
| Formula Weight | 355.45 |
PSB-12062, MedChemExpress
MedChemExpress PSB-12062 is a potent and selective P2X4 antagonist with an IC50 of 1.38 μM for human P2X4.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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| Molecular Weight (g/mol) | 337.39 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | PSB-12062 |
| Grade | Research |
| SMILES | O=S(N1C2=C(C=CC=C2)OC3=CC=CC=C13)(C4=CC=C(C)C=C4)=O |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 99.06% |
| CAS | 55476-47-6 |
| Solubility Information | DMSO : 25 mg/mL (74.10 mM; Need ultrasonic) |
| Health Hazard 1 | H302 |
| Synonym | N-(p-Methylphenylsulfonyl)phenoxazine |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H15NO3S |
| Formula Weight | 337.39 |
NMS-859, MedChemExpress
MedChemExpress NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.
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| Molecular Weight (g/mol) | 349.79 |
|---|---|
| Color | Gray |
| Physical Form | Solid |
| Chemical Name or Material | NMS-859 |
| Grade | Research |
| SMILES | O=S1(C2=CC=CC=C2C(NC3=CC(NC(CCl)=O)=CC=C3)=N1)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.01% |
| CAS | 1449236-96-7 |
| Solubility Information | DMSO : ≥ 42 mg/mL (120.07 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H12ClN3O3S |
| Formula Weight | 349.79 |
Terutroban, MedChemExpress
MedChemExpress Terutroban is a thromboxane-prostaglandin receptor antagonist.
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| Molecular Weight (g/mol) | 407.91 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Terutroban |
| Grade | Research |
| SMILES | O=C(O)CCC1=C2CC[C@@H](NS(=O)(C3=CC=C(Cl)C=C3)=O)CC2=CC=C1C |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 95.0% |
| CAS | 165538-40-9 |
| Solubility Information | DMSO : ≥ 22 mg/mL (53.93 mM) |
| Synonym | S-18886 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C20H22ClNO4S |
| Formula Weight | 407.91 |
HJC0350, MedChemExpress
MedChemExpress HJC0350 is a potent and specific EPAC2 antagonist with an IC50 of 0.3 μM.
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| Molecular Weight (g/mol) | 277.38 |
|---|---|
| Color | Pink |
| Physical Form | Solid |
| Chemical Name or Material | HJC0350 |
| Grade | Research |
| SMILES | O=S(N1C(C)=CC(C)=C1)(C2=C(C)C=C(C)C=C2C)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 99.52% |
| CAS | 885434-70-8 |
| Solubility Information | DMSO : 33.33 mg/mL (120.16 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H19NO2S |
| Formula Weight | 277.38 |