Benzenesulfonamides
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Filtered Search Results
FASN-IN-4, MedChemExpress
MedChemExpress FASN-IN-4 is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 also inhibits SARS-CoV-2 with an EC50 of 18.6 nM.
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AKR1C3-IN-1, MedChemExpress
MedChemExpress AKR1C3-IN-1 is a potent, highly selective inhibitor of AKR1C3, with an IC50 of 13 nM.
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| Molecular Weight (g/mol) | 317.36 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | AKR1C3-IN-1 |
| Grade | Research |
| SMILES | O=S(N1CC2=CC=CC=C2CC1)(C3=CC(C(O)=O)=CC=C3)=O |
| Percent Purity | 98.74% |
| CAS | 327092-81-9 |
| Solubility Information | DMSO : ≥ 100 mg/mL (315.10 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H15NO4S |
| Formula Weight | 317.36 |
GSK8612, MedChemExpress
MedChemExpress GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6.8 for recombinant TBK1.
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| Molecular Weight (g/mol) | 520.33 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | GSK8612 |
| Grade | Research |
| SMILES | NS(C1=CC=C(CNC2=C(Br)C=NC(NC3=CN(CC(F)(F)F)N=C3C)=N2)C=C1)(=O)=O |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.37% |
| CAS | 2361659-62-1 |
| Solubility Information | DMSO : ≥ 125 mg/mL (240.23 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | -20°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Shelf Life | -20°C, protect from light∣In solvent : -80°C, 6 months∣-20°C, 1 month (protect from light) |
| Molecular Formula | C17H17BrF3N7O2S |
| Formula Weight | 520.33 |
Alofanib, MedChemExpress
MedChemExpress Alofanib (RPT835) is a potent and selective allosteric inhibitor of fibroblast growth factor receptor 2 (FGFR2). Anticancer and antiangiogenic activity.
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| Molecular Weight (g/mol) | 413.4 |
|---|---|
| Color | Yellow |
| Physical Form | Solid |
| Chemical Name or Material | Alofanib |
| Grade | Research |
| SMILES | O=C(O)C1=CC=CC(S(=O)(NC2=CC(C3=CC=CN=C3)=C(C)C=C2[N+]([O-])=O)=O)=C1 |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.81% |
| CAS | 1612888-66-0 |
| Solubility Information | DMSO : ≥ 30.1 mg/mL (72.81 mM) |
| Synonym | RPT835 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H15N3O6S |
| Formula Weight | 413.4 |
PKR-IN-2, MedChemExpress
MedChemExpress PKR-IN-2 is a pyruvate kinase isoform PKR activator extracted from patent WO2014139144A1, compound 160. PKR-IN-2 can be used for the research of PKR function related diseases, including cancer, diabetes, obesity, autoimmune disorders, and benign prostatic hyperplasia.
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| Molecular Weight (g/mol) | 468.57 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | PKR-IN-2 |
| Grade | Research |
| SMILES | N1C2C(=C(S(NC3=CC=C(C(N4CCC(O)(CC(C)C)CC4)=O)C=C3)(=O)=O)C=CC=2)N=CC=1 |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 95.14% |
| CAS | 1628428-01-2 |
| Solubility Information | DMSO : 50 mg/mL (106.71 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C24H28N4O4S |
| Formula Weight | 468.57 |
Hydroxyhexamide, MedChemExpress
MedChemExpress Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agents.
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| Molecular Weight (g/mol) | 326.41 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Hydroxyhexamide |
| Grade | Research |
| SMILES | O=S(C1=CC=C(C(O)C)C=C1)(NC(NC2CCCCC2)=O)=O |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 99.68% |
| CAS | 3168-01-2 |
| Solubility Information | DMSO : ≥ 300 mg/mL (919.09 mM) |
| Synonym | (±)-Hydroxyhexamid |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H22N2O4S |
| Formula Weight | 326.41 |
HMN-176, MedChemExpress
MedChemExpress HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1), without significant effect on tubulin polymerization.
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| Molecular Weight (g/mol) | 382.43 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | HMN-176 |
| Grade | Research |
| SMILES | O=S(C1=CC=C(OC)C=C1)(NC2=CC=CC=C2/C=C/C3=CC=N(C=C3)=O)=O |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.54% |
| CAS | 173529-10-7 |
| Solubility Information | DMSO : ≥ 30 mg/mL (78.45 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C20H18N2O4S |
| Formula Weight | 382.43 |
Orexin 2 Receptor Agonist, MedChemExpress
MedChemExpress Orexin 2 Receptor Agonist is a potent (EC50 on OX2R is 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio is 70) agonist.
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| Molecular Weight (g/mol) | 586.7 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Orexin 2 Receptor Agonist |
| Grade | Research |
| SMILES | O=C(C1=CC=CC(C)=C1)NCCNC2=CC(NS(C3=C(OC)C=CC(C4=CC(C(N(C)C)=O)=CC=C4)=C3)(=O)=O)=CC=C2 |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 99.75% |
| CAS | 1796565-52-0 |
| Solubility Information | DMSO : ≥ 32 mg/mL (54.54 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C32H34N4O5S |
| Formula Weight | 586.7 |
LX2343, MedChemExpress
MedChemExpress LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance.
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| Molecular Weight (g/mol) | 474.91 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | LX2343 |
| Grade | Research |
| SMILES | O=C(NC1=CC=C(OCO2)C2=C1)CN(C3=CC(Cl)=CC=C3OC)S(=O)(C4=CC=CC=C4)=O |
| For Use With (Application) | Neuroscience-Neurodegeneration |
| Percent Purity | 99.74% |
| CAS | 333745-53-2 |
| Solubility Information | DMSO : ≥ 100 mg/mL (210.57 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C22H19ClN2O6S |
| Formula Weight | 474.91 |
L755507, MedChemExpress
MedChemExpress L755507 is a potent, selective agonist of β3-AR with an IC50 of 35 nM. L755507 enhances the homology-directed repair (HDR)-mediated genome editing in CRISPR/Cas9 nickase system.
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PF-06471553, MedChemExpress
MedChemExpress PF-06471553 is a potent, selective and orally available monoacylglycerol acyltransferase 3 (MGAT3) inhibitor, with an IC50 of 92 nM.
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| Molecular Weight (g/mol) | 467.54 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | PF-06471553 |
| Grade | Research |
| SMILES | O=S(C1=CC2=C(CN(C(CC3=CC=CC(OC)=C3)=O)C2)C=C1)(NC4=NN(C5CCC5)N=C4)=O |
| For Use With (Application) | Metabolism-sugar/lipid metabolism |
| Percent Purity | 98.18% |
| CAS | 1808094-07-6 |
| Solubility Information | DMSO : ≥ 150 mg/mL (320.83 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C23H25N5O4S |
| Formula Weight | 467.54 |
Etebenecid, MedChemExpress
MedChemExpress Etebenecid is a uricosuric agents, lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys, also inhibits penicillin tubular secretion.
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Acetohexamide, MedChemExpress
MedChemExpress Acetohexamide is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2; stimulate the pancreas to secrete insulin.
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| Molecular Weight (g/mol) | 324.4 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Acetohexamide |
| Grade | Research |
| SMILES | O=S(C1=CC=C(C(C)=O)C=C1)(NC(NC2CCCCC2)=O)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 99.39% |
| CAS | 968-81-0 |
| Solubility Information | DMSO : 25 mg/mL (77.07 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H20N2O4S |
| Formula Weight | 324.4 |
SU11274, MedChemExpress
MedChemExpress SU11274 is a selective Met inhibitor with IC50 of 10 nM, but has no effects on PGDFRβ, EGFR or Tie2.
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| Molecular Weight (g/mol) | 568.09 |
|---|---|
| Color | Orange |
| Physical Form | Solid |
| Chemical Name or Material | SU11274 |
| Grade | Research |
| SMILES | O=S(C1=CC2=C(C=C1)NC(/C2=C/C3=C(C(C(N4CCN(CC4)C)=O)=C(N3)C)C)=O)(N(C)C5=CC=CC(Cl)=C5)=O |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.19% |
| CAS | 658084-23-2 |
| Solubility Information | DMSO : ≥ 100 mg/mL (176.03 mM) |
| Synonym | PKI-SU11274 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C28H30ClN5O4S |
| Formula Weight | 568.09 |
Veralipride, MedChemExpress
MedChemExpress Veralipride is a D2 receptor antagonist. It is an alternative antidopaminergic treatment for menopausal symptoms.
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| Molecular Weight (g/mol) | 383.46 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Veralipride |
| Grade | Research |
| SMILES | O=C(NCC1N(CC=C)CCC1)C2=CC(S(=O)(N)=O)=CC(OC)=C2OC |
| For Use With (Application) | Neuroscience-Neurodegeneration |
| Percent Purity | 99.57% |
| CAS | 66644-81-3 |
| Solubility Information | DMSO : ≥ 100 mg/mL (260.78 mM) |
| Synonym | (±)-Veralipride LIR166 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C17H25N3O5S |
| Formula Weight | 383.46 |