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Invitrogen™ ZPK Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5100731
This item is not returnable.
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Description
Antibody detects endogenous levels of total MAP3K12.
ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.
Specifications
| ZPK | |
| Polyclonal | |
| Unconjugated | |
| MAP3K12 | |
| DLK; Dual leucine zipper bearing kinase; dual leucine zipper kinase; dual leucine zipper kinase DLK; leucine zipper protein kinase; leucine-zipper protein kinase; M3KC; MAP3K12; MAPK-upstream kinase; MEKK12; Mitogen activated protein kinase 12 (Zipper (leucine) protein kinase); mitogen activated protein kinase kinase kinase 12; mitogen-activated protein kinase kinase kinase 12; Mixed lineage kinase; MUK; PK; protein kinase MUK; zipper (leucine) protein kinase; Zpk; ZPKP1 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 25579, 26404, 7786 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q12852, Q60700, Q63796 | |
| MAP3K12 | |
| A synthesized peptide derived from human MAP3K12(Accession Q12852), corresponding to amino acid residues R8-P58. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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