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Invitrogen™ ZHX2 Polyclonal Antibody
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Product Code. 15780321 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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15780321 100 μL 100µL
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Product Code. 15780321 Supplier Invitrogen™ Supplier No. PA552373

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PQEYDQLAAK TGLVRTEIVR WFKENRCLLK TGTVKWMEQY QHQPMADDHG YDAVARKATK PMAESPKNGG DVVPQYYKDP KKLCEEDLEK LVTRVKVGSE PAKDCLPAKP SEATSDRSEG SSRDGQGSDE NEESSVVDYV Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 74%.

Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZHX2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ZHX2
Gene Accession No. Q9Y6X8
Gene Alias AFP regulator 1; AFR1; Afr-1; alpha fetoprotein regulation 1, adult; alpha-fetoprotein regulator 1; KIAA0854; LOW QUALITY PROTEIN: zinc fingers and homeoboxes protein 2; mKIAA0854; Raf; Regulator of AFP; transcription factor ZHX2; Zhx2; Zinc finger and homeodomain protein 2; zinc fingers and homeoboxes 2; zinc fingers and homeoboxes protein 2; zinc-fingers and homeoboxes 2
Gene Symbols ZHX2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ZHX2. Recombinant protein control fragment (Product #RP-89410).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22882
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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