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Tocris Bioscience™ XAP 044
GREENER_CHOICE

Potent and selective mGlu7 antagonist

Brand:  Tocris Bioscience™ 5248/50

Encompass

Product Code. 15766616

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Description

Description

XAP 044 is a potent and selective mGlu7 antagonist (IC50 = 88 nM); inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice. Displays no effects on the LTP of mGlu7 deficient mice. Exhibits novel activity by binding to the mGlu7 Venus flytrap domain (VFTD). Exhibits anti-anxiety effects in rodent models. Brain penetrant.
Specifications

Specifications

>98%
50 mg
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