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WZ-3146, MedChemExpress

Product Code. 16414908
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Product Code. 16414908 Supplier Medchem Express Supplier No. HY12001

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Description

MedChemExpress WZ3146 is a mutant selective EGFR inhibitor with IC50s of 2, 2, 5, 14 and 66 nM for EGFRL858R, EGFRL858R/T790M, EGFRE746_A750, EGFRE746_A750/T790M and EGFR, respectively.

WZ3146 is a mutant selective EGFR inhibitor with IC50s of

Specifications

Chemical Name or Material WZ-3146
CAS 1214265-56-1
Color Off-White
Purity Grade Notes Research
Molecular Formula C24H25ClN6O2
Quantity 10 mg
Solubility Information DMSO : 62.5 mg/mL (134.42 mM; ultrasonic and warming and heat to 60°C)
SMILES CN1CCN(C2=CC=C(C=C2)NC3=NC=C(C(OC4=CC(NC(C=C)=O)=CC=C4)=N3)Cl)CC1
Molecular Weight (g/mol) 464.95
Formula Weight 464.95
Percent Purity 99.11%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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