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WIKI4, MedChemExpress

Product Code. 16439737
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Product Code. 16439737

Brand: Medchem Express HY16910

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Description

MedChemExpress WIKI4 is a potent tankyrase inhibitor with an IC50 of 26 nM for TNKS2. WIKI4 potently inhibits Wnt/β-catenin signaling and that its half-maximal response dose is 75 nM. WIKI4 mediates its effects on Wnt/β-catenin signaling by inhibiting the enzymatic activity of TNKS2. WIKI4 is cytotoxic to SCLC cells with an IC50 value of 0.02 μM.

WIKI4 is a potent tankyrase inhibitor with an IC50 of 26 nM for TNKS2. WIKI4 potently inhibits Wnt/β-catenin signaling and that its half-maximal response dose is 75 nM. WIKI4 mediates its effects on Wnt/β-catenin signaling by inhibiting the enzymatic activity of TNKS2. WIKI4 is cytotoxic to SCLC cells with an IC50 value of 0.02 μM.

Specifications

Chemical Name or Material WIKI4
CAS 838818-26-1
Color Tan
Purity Grade Notes Research
Molecular Formula C29H23N5O3S
Quantity 5 mg
Solubility Information DMSO : 6.8 mg/mL (13.04 mM; Need ultrasonic and warming)
SMILES O=C1N(CCCSC2=NN=C(C3=CC=NC=C3)N2C4=CC=C(OC)C=C4)C(C5=CC=CC6=CC=CC1=C56)=O
Molecular Weight (g/mol) 521.59
Formula Weight 521.59
Percent Purity 99.93%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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