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STEMCELL Technologies WHI-P154

Product Code. 17150242
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Quantity:
10 mg
Unit Size:
10mg
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Product Code. 17150242

Brand: STEMCELL Technologies 73552

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This item is not returnable. View return policy

Description

JAK/STAT pathway inhibitor; Inhibits JAK3

  • WHI-P154 is an inhibitor of Janus kinase 3 (JAK3) with IC50 values of 28 and 128 μM against human and mouse proteins, respectively (Sudbeck et al.) It has also been reported to show significant inhibition of other kinases, including epidermal growth factor receptor (EGFR) in the nanomolar range (Changelian et al.; Uckun et al.) No significant inhibition of JAK1 or JAK2 has been observed (Sudbeck et al.)

Specifications

CAS 211555-04-3
Synonym JAK3 Inhibitor II; Janus-Associated Kinase 3 Inhibitor II
Quantity 10 mg
Molecular Formula C16H14BrN3O3
Purity ≥98%
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