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VU0650786, MedChemExpress

Product Code. 16400577
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Product Code. 16400577 Supplier Medchem Express Supplier No. HY108710

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Description

MedChemExpress VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents.

VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents.

Specifications

Chemical Name or Material VU0650786
CAS 1809085-30-0
Color Off-White
Purity Grade Notes Research
Molecular Formula C18H15ClFN5O2
Quantity 50 mg
Solubility Information DMSO : 250 mg/mL (644.66 mM; Need ultrasonic)
SMILES ClC1=CN=C(OCC2=NN([C@H](C)CN(C3=C(F)N=CC=C3)C4=O)C4=C2)C=C1
Molecular Weight (g/mol) 387.8
Formula Weight 387.8
Percent Purity 99.16%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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