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VU0361737, MedChemExpress

Product Code. 16486456
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Product Code. 16486456 Supplier Medchem Express Supplier No. HY14418

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Description

MedChemExpress VU0361737 (ML-128) is a potent, selective and CNS penetrant positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4 PAM), with EC50s of 240 nM and 110 nM for human and rat mGluR4 receptors, respectively. VU0361737 has neuroprotective effect. VU0361737 is potential for Parkinson's disease research.

VU0361737 (ML-128) is a potent, selective and CNS penetrant positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4 PAM), with EC50s of 240 nM and 110 nM for human and rat mGluR4 receptors, respectively. VU0361737 has neuroprotective effect. VU0361737 is potential for Parkinson's disease research.

Specifications

Chemical Name or Material VU0361737
CAS 1161205-04-4
Color White
Purity Grade Notes Research
Molecular Formula C13H11ClN2O2
Quantity 100 mg
Synonym ML-128
Solubility Information DMSO : 100 mg/mL (380.68 mM; Need ultrasonic)
SMILES ClC(C=C1)=C(OC)C=C1NC(C2=NC=CC=C2)=O
Molecular Weight (g/mol) 262.69
Formula Weight 262.69
Percent Purity 99.83%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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