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MMAF-OMe, MedChemExpress

Product Code. 16420366
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Product Code. 16420366 Supplier Medchem Express Supplier No. HY79256

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Description

MedChemExpress MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. MMAF-Ome inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively.

MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. MMAF-Ome inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively.

Specifications

Chemical Name or Material MMAF-OMe
CAS 863971-12-4
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C40H67N5O8
Quantity 2 mg
Synonym Monomethyl auristatin F methyl ester
Solubility Information DMSO : ≥ 100 mg/mL (134.05 mM)
SMILES CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C(OC)=O)CC2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C
Molecular Weight (g/mol) 745.99
Formula Weight 745.99
Percent Purity 96.68%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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