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Invitrogen™ ULK2 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA522173

Product Code. 13279468

  • 568.00 € / 100µg

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Description

Description

Recommended positive controls: 293T, A431, HeLa, HepG2, NT2D1, NIH-3T3. Predicted reactivity: Mouse (94%), Rat (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ULK2
Polyclonal
Unconjugated
ULK2
A830085I22Rik; ATG1B; AU015340; EC:2.7.11.1; KIAA0623; mKIAA0623; serine/threonine-protein kinase ULK2; Serine/threonine-protein kinase Unc51.2; ULK2; unc-51 like autophagy activating kinase 2; unc-51 like kinase 2; Unc51.2; unc-51-like kinase 2
Rabbit
Antigen affinity chromatography
RUO
29869, 9706
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.21 mg/mL
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Q8IYT8, Q9QY01
ULK2
Recombinant protein encompassing a sequence within the C-terminus region of human ULK2. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse
Antibody
IgG
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