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Invitrogen™ TWIST1 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA586070

Product Code. 16372975

  • 512.00 € / 100µL

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Description

Description

Purity is > 95% by SDS-PAGE.

TWIST1 acts as a transcriptional regulator. It inhibits myogensis by sequestering E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. TWIST1 also represses proinflammatory cytokines such as TNFA and IL1B. TWIST also regulates cranial suture patterning and fusion and gene expression differentially depending on dimer composition. Mutations in the gene are implicated in Saethre-Chotzen syndrome, a disease characterized by coronal synostosis, brachycephaly, low front hairline, facial asymmetry, hypertelorism, broad halluces, and clinodactyly.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TWIST1
Polyclonal
Unconjugated
TWIST1
AA960487; ACS3; B-HLH DNA binding protein; bHLHa38; BPES2; BPES3; charlie chaplin; class A basic helix-loop-helix protein 38; CRS; CRS1; CSO; H-twist; M-twist; p ACS3; Pde; pdt; Pluridigite; polydactyly EMS; SCS; Ska>m10Jus>; Ska>sup>m10Jus>/sup>; Ska10; Twist; twist basic helix-loop-helix transcription factor 1; twist family bHLH transcription factor 1; twist gene homolog 1; twist homolog 1; TWIST homolog of drosophila; Twist1; twist-related protein 1
Rabbit
Antigen Affinity Chromatography
RUO
22160, 7291
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
P26687, Q15672
TWIST1
A synthetic peptide corresponding to amino acids 1-50 of Human TWIST1.
100 μL
Primary
Human, Mouse
Antibody
IgG
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