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Tubastatin A Hydrochloride, MedChemExpress

Product Code. 16476146
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Product Code. 16476146

Brand: Medchem Express HY13271

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Description

MedChemExpress Tubastatin A Hydrochloride (Tubastatin A HCl) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A Hydrochloride also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2).

Tubastatin A Hydrochloride (Tubastatin A HCl) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A Hydrochloride also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2).

Specifications

Chemical Name or Material Tubastatin A Hydrochloride
CAS 1310693-92-5
Color Off-White
Purity Grade Notes Research
Molecular Formula C20H22ClN3O2
Quantity 100 mg
Synonym Tubastatin A HCl TSA HCl
Solubility Information DMSO : 10.8 mg/mL (29.04 mM; Need ultrasonic and warming) ∣H2O : 6.67 mg/mL (17.94 mM; Need ultrasonic)
SMILES O=C(C1=CC=C(C=C1)CN2C3=C(C4=C2C=CC=C4)CN(C)CC3)NO.[H]Cl
Molecular Weight (g/mol) 371.86
Formula Weight 371.86
Percent Purity 97.17%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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