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  6. Invitrogen™ TRAIL-R3 Monoclonal Antibody (C1), Invitrogen™

Invitrogen™ TRAIL-R3 Monoclonal Antibody (C1), Invitrogen™
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Product Code. 17958912
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200 μL
Unit Size:
200µL
20µL
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Product Code. Quantity unitSize
17958912 200 μL 200µL
17969202 20 μL 20µL
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Product Code. 17958912 Supplier Invitrogen™ Supplier No. MA551033

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Description

Mouse Monoclonal Antibody

TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
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Specifications

Antigen TRAIL-R3
Applications Western Blot
Classification Monoclonal
Clone C1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4
Gene TNFRSF10C
Gene Accession No. O14798
Gene Alias Antagonist decoy receptor for TRAIL/Apo-2L; CD263; cytotoxic TRAIL receptor-3; DCR1; DCR1-TNFR; Decoy receptor 1; decoy TRAIL receptor without death domain; LIT; lymphocyte inhibitor of TRAIL; MGC149501; MGC149502; TNF receptor superfamily member 10c; TNF-related apoptosis-inducing ligand receptor 3; TNFRSF10C; TRAIL receptor 3; TRAIL receptor without an intracellular domain; TRAILR3; TRAIL-R3; TRID; Tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; UNQ321/PRO366
Gene Symbols TNFRSF10C
Host Species Mouse
Immunogen Recombinant Human TNFRSF10C protein, Glu32-Thr244 (Accession #O14798).
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8794
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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