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Torin 2, MedChemExpress

Product Code. 16461647
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Product Code. 16461647

Brand: Medchem Express HY13002

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Description

MedChemExpress Torin 2 is an mTOR inhibitor with EC50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC50: 200 nM). Torin 2 also inhibits DNA-PK with an IC50 of 0.5 nM in the cell free assay. Torin 2 can suppress both mTORC1 and mTORC2.

Torin 2 is an mTOR inhibitor with EC50 of 0.25 nM for inhibiting cellular mTOR activity, and exhibits 800-fold selectivity over PI3K (EC50: 200 nM). Torin 2 also inhibits DNA-PK with an IC50 of 0.5 nM in the cell free assay. Torin 2 can suppress both mTORC1 and mTORC2.

Specifications

Chemical Name or Material Torin 2
CAS 1223001-51-1
Color Yellow
Purity Grade Notes Research
Molecular Formula C24H15F3N4O
Quantity 50 mg
Solubility Information DMSO : 15.62 mg/mL (36.12 mM; Need ultrasonic)
SMILES O=C1N(C2=C(C=C1)C=NC3=CC=C(C=C32)C4=CC=C(N=C4)N)C5=CC=CC(C(F)(F)F)=C5
Molecular Weight (g/mol) 432.4
Formula Weight 432.4
Percent Purity 98.51%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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