missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 13209148

Invitrogen™ TMEM59 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA521575

Product Code. 13209148

  • 516.00 € / 100µg

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Description

Recommended positive controls: A431, mouse liver, rat kidney. Predicted reactivity: Mouse (95%), Rat (94%), Pig (96%), Chicken (83%), Rhesus Monkey (98%), Chimpanzee (100%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TMEM59
Polyclonal
Unconjugated
TMEM59
1110001M20Rik; 3110046P06Rik; AI256529; C1orf8; D4Ertd20e; DCF1; dendritic cell factor 1; HSPC001; Liver membrane-bound protein; MTDCF1; ORF18; PRO195; RGD1310313; RP4-758J24.2; Tdcf1; Thymic dendritic cell-derived factor 1; TMEM59; Transmembrane protein 59; UNQ169; UNQ169/PRO195
Rabbit
Antigen affinity chromatography
RUO
100196907, 56374, 9528
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q9BXS4, Q9QY73
TMEM59
Recombinant protein encompassing a sequence within the center region of human TMEM59. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.