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  5. Tocris Bioscience™ TL4-12

Tocris Bioscience™ TL4-12
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Product Code. 18784739
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18784739

Brand: Tocris Bioscience™ 5910/10

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This item is not returnable. View return policy

Description

Potent MAP4K2 (GCK) inhibitor

TL4-12 is a potent MAP4K2 (GCK) inhibitor (IC50 = 37 nM). Exhibits >70-fold selectivity for MAP4K2 over TAK1 (IC50 = 2.7 μM for TAK1). Inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation, in vitro.
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Specifications

Chemical Name or Material 4-Methyl-3-[[6-(methylamino)-4-pyrimidinyl]oxy]-N-[3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)phenyl]benzamide
CAS 1620820-12-3
Quantity 10 mg
Molecular Formula C25H27F3N6O2
Purity 98%
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