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Tocris Bioscience™ TDI 11861

Product Code. 18054702
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5 mg
Unit Size:
5mg
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Product Code. 18054702 Supplier Tocris Bioscience™ Supplier No. 8036/5

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Description

Soluble adenylyl cyclase inhibitor

TDI 11861 is a potent and selective soluble adenylyl cyclase (sAC) inhibitor (IC50 values are 3.3 nM and 5.5 nM in biochemical and cellular assays, respectively; Kd = 1.4 nM). Inhibits cellular sAC-specific cAMP accumulation (IC50 = 7 nM) and blocks sperm capacitation in vitro. Cell permeable, not cytotoxic and suitable for both in vivo and in vitro use.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (3R)-4-[2-[2-[[3-(2-Amino-6-chloro-4-pyrimidinyl)-1-(difluoromethyl)-1H-pyrazol-4-yl]methyl]phenoxy]ethyl]-3-morpholinemethanol
CAS 2857049-72-8
Quantity 5 mg
Target Adenylyl Cyclase Inhibitors
Molecular Formula C22H25ClF2N6O3
Purity 98%
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