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TC-S 7009, Tocris Bioscience™
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High affinity and selective HIF-2α inhibitor

Brand:  Tocris Bioscience 5243/5

Encompass

Product Code. 15903221

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Description

Description

TC-S 7009 is a high affinity and selective HIF-2α inhibitor (Kd = 81 nM). Binds to the HIF-2α PAS-B domain; disrupts HIF-2α-ARNT heterodimerization. Exhibits >60-fold selectivity for HIF-2α over HIF-1α. Decreases HIF-2α DNA-binding and attenuates expression of HIF-2α target genes in vitro.
Specifications

Specifications

N-(3-Chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine
1422955-31-4
>99%
5 mg
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