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  5. Tocris Bioscience™ TC-S 7006

Tocris Bioscience™ TC-S 7006
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Product Code. 18797058
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Quantity:
50 mg
Unit Size:
50mg
This item is not returnable. View return policy

Product Code. 18797058

Brand: Tocris Bioscience™ 5240/50

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This item is not returnable. View return policy

Description

Potent and selective Tpl2 (Cot; MAP3K8) inhibitor

TC-S 7006 is a potent and selective Tpl2 (Cot; MAP3K8) inhibitor (IC50 = 50 nM). Selective for Tpl2 over MEK, p38, Src, MK2, PKC and EGFR. Inhibits LPS-induced TNF-α secretion from monocytes and attenuates acute myeloid leukemia (AML) cell proliferation in vitro. Also reduces cytolytic activity of human CD8+ cytotoxic T lymphocytes. Cell permeable.
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Specifications

Quantity 50 mg
Product Type TC-S 7006
Purity >99%
Molecular Weight (g/mol) 404.83
Inhibitors TC-S 7006

For Research Use Only

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