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Thermo Scientific™ Tango™ CXCR3-bla U2OS Cells

Product Code. 10471215
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Quantity:
8 x 106 Cells
Unit Size:
Each
This item is not returnable. View return policy

Product Code. 10471215

Brand: Thermo Scientific™ K1829

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Description

The Tango™ CXCR3-bla U2OS cells contain the human chemokine (C-X-C motif) receptor 3 (CXCR3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.

This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ CXCR3-bla U2OS cells are functionally validated for Z' and EC50 concentrations of I-TAC (CXCL11). In addition, Tango™ CXCR3-bla U2OS cells have been tested for assay performance under variable conditions. This data are found in the Validation & Assay Performance Summary.

TRUSTED_SUSTAINABILITY

Specifications

Accession Number NM_001504
Assay Entry Cell-based beta-arrestin recruitment
Cell State Dividing Cells
Content And Storage Contents:
K1829 Tango™ CXCR3-bla U2OS cells
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).
Includes:
• Tango™ CXCR3-bla U2OS cells
• Tango™ CXCR3-bla U2OS Assay Protocol
• Certificate of Analysis

Storage:
The Tango™ CXCR3-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Cytoplasmic Tail Native Tail
Detection Method Fluorescence
For Use With (Application) FRET
Gene Symbol CXCR3
Human Protein Class G-Protein Coupled Receptor (GPCR)
Population Status Single Cell Clone Origin
Product Line GeneBLAzer, Tango
Quantity 8 x 106 Cells
Readout End Point
Target Entry CXCR3
Type U2OS Cell
Cell Line U2OS
System Type Tango™
Druggable Target GPCR
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For Research Use Only. Not for use in diagnostic procedures.

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