missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Pyrroles
  7. TAK-285, MedChemExpress

TAK-285, MedChemExpress

Product Code. 16496358
Encompass_Preferred
Click to view available options
Quantity:
5 mg
10 mg
50 mg
Unit Size:
10mg
50mg
5mg
This item is not returnable. View return policy

Product Code. 16496358

Brand: Medchem Express HY15196

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress TAK-285 is a potent, selective, ATP-competitive and orally active HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, respectively. TAK-285 is >10-fold selectivity for HER1/2 than HER4, and less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. TAK-285 has effective antitumor activity. TAK-285 can cross the blood-brain barrier (BBB).

TAK-285 is a potent, selective, ATP-competitive and orally active HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, respectively. TAK-285 is >10-fold selectivity for HER1/2 than HER4, and less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. TAK-285 has effective antitumor activity. TAK-285 can cross the blood-brain barrier (BBB).

Specifications

Chemical Name or Material TAK-285
CAS 871026-44-7
Color Off-White
Purity Grade Notes Research
Molecular Formula C26H25ClF3N5O3
Quantity 10 mg
Solubility Information DMSO : ≥ 50 mg/mL (91.25 mM)
SMILES ClC(C=C(NC1=NC=NC2=C1N(CCNC(CC(C)(C)O)=O)C=C2)C=C3)=C3OC4=CC=CC(C(F)(F)F)=C4
Molecular Weight (g/mol) 547.96
Formula Weight 547.96
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
Show More Show Less

Research purposes only

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.