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Description
Immunogen sequence: LLSLSYLPTA ERLTVVVVKA KNLIWTNDKT TADPFVKVYL LQDGRKMSKK KTAVKRDDPN PVFNEAMIFS VPAIVLQDLS LRVTVAESSS DGRGDNVGHV IIGPSASGMG TTHWNQMLAT LRRPVSMWHA V Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 98%.
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.
Specifications
Specifications
| Antigen | SYT12 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | SYT12 |
| Gene Accession No. | Q8IV01 |
| Gene Alias | Srg1; synaptotagmin 12; synaptotagmin XII; Synaptotagmin12; Synaptotagmin-12; synaptotagmin-related gene 1 protein; SynaptotagminXII; synaptotagmin-XII; Syt XII; SYT11; Syt12; SYT-12; Sytr1; SytXII |
| Gene Symbols | SYT12 |
| Show More |
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