missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Fluorobenzenes
  8. Sulindac, MedChemExpress

Sulindac, MedChemExpress

Product Code. 16478056
Encompass_Preferred
Click to view available options
Quantity:
100 mg
500 mg
Unit Size:
100mg
500mg
This item is not returnable. View return policy

Product Code. 16478056

Brand: Medchem Express HYB0008

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress Sulindac (MK-231) is an orally active nonsteroidal anti-inflammatory agent.

Sulindac is used to reduce pain, swelling, and joint stiffness from arthritis. Sulindac is also used for the research of arthritis of the spine, gouty arthritis. Sulindac, as an immunomodulatory agent, can downregulate PD-L1 through the blockade of NF-κB signaling and modulates the response of pMMR colorectal cancer (CRC) to anti-PD-L1 immunotherapy, inhibits the development and progression of colorectal cancer CRC. Sulindac also inhibits TGF-β1- induced epithelial-mesenchymal transition (EMT) and suppresses lung cancer cell migration and invasion via downregulation of SIRT1.

Specifications

Chemical Name or Material Sulindac
CAS 38194-50-2
Color Yellow
Purity Grade Notes Research
Molecular Formula C20H17FO3S
Quantity 100 mg
Synonym MK-231
Solubility Information DMSO : 100 mg/mL (280.58 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(CC(C1=C2C=CC(F)=C1)=C(/C2=C/C3=CC=C(C=C3)S(C)=O)C)O
Molecular Weight (g/mol) 356.41
Formula Weight 356.41
Percent Purity 99.34%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
Show More Show Less

Research purposes only

Product Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.