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STK38 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA513831
This item is not returnable.
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Description
STK38 (also known as NDR) or Nuclear Dbf2-related protein is a serine/threonine kinase in the subgroup of the AGC kinase family that is regulated by Mob proteins. Fas and TNFα receptor stimulation activates human STK38 by promoting phosphorylation at the hydrophobic motif. NDR acts as a novel pro-apoptotic kinase, and is a key member of the RASSF1A/MST1 signaling cascade. STK38 is crucial for the fidelity of mitotic chromosome alignment in mammalian cells. STK38 is incorporated into the HIV-1 particles and is cleaved by the HIV-1 protease. STK38-driven centrosome duplication requires Cdk2 activity, and Cdk2-induced centrosome amplification is affected upon reduction of STK38 activity.
Specifications
| STK38 | |
| Polyclonal | |
| PBS with 0.09% sodium azide | |
| Q15208 | |
| STK38 | |
| KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human STK38 | |
| 400 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Western Blot | |
| Unconjugated | |
| STK38 | |
| 5830476G13Rik; 9530097A09Rik; AA617404; NDR; Ndr Ser/Thr kinase-like protein; NDR1; NDR1 protein kinase; nuclear Dbf2-related kinase 1; serine/threonine kinase 38; serine/threonine-protein kinase 38; STK38 | |
| Rabbit | |
| Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
| RUO | |
| 11329 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |