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Spironolactone, MedChemExpress

Product Code. 16480998
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5 g
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Product Code. 16480998 Supplier Medchem Express Supplier No. HYB0561

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Description

MedChemExpress Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes.

Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes.

Specifications

Chemical Name or Material Spironolactone
CAS 52-01-7
Color White
Purity Grade Notes Research
Molecular Formula C24H32O4S
Quantity 5 g
Synonym SC9420
Solubility Information DMSO : ≥ 50 mg/mL (120.03 mM) ∣H2O : 0.1 mg/mL (0.24 mM; Need ultrasonic)
SMILES C[C@@]12[C@](OC3=O)(CC3)CC[C@@]1([H])[C@@]([C@@H](CC4=CC5=O)SC(C)=O)([H])[C@]([C@]4(CC5)C)([H])CC2
Molecular Weight (g/mol) 416.57
Formula Weight 416.57
Percent Purity 99.58%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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