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Invitrogen™ Human SNF1LK2, GST Tag Recombinant Protein

Artikelnummer. 15428673
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Quantity:
10 μg
100 μg
Packungsgröße:
100µg
Each
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For Research Use Only. All usage must comply with product instructions.

Artikelnummer. 15428673

Marke: Invitrogen™ PR8353A

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Dieser Artikel kann nicht zurückgegeben werden. Rückgaberichtlinie anzeigen

For Research Use Only. All usage must comply with product instructions.

Beschreibung

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

SNF1LK2 (QIK) is a serine/threonine kinase and is a salt-inducible kinase that belongs to the AMP-activated protein kinase family. SNF1LK2 negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1'alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.
TRUSTED_SUSTAINABILITY

Spezifikation

Accession Number Q9H0K1
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris with 2mM DTT, 0.04% Triton X-100, 150mM NaCl, 0.5mM EDTA, 50% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 23235
Molecular Weight (g/mol) 131.4 kDa
Name Human SNF1LK2, GST Tag
pH Range 7.5
Purification Method Purified
Quantity 100 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias G630080D20Rik; KIAA0781; LOH11CR1I; QIK; Qin-induced kinase; RGD1559698; salt induceable kinase 2; salt inducible kinase 2; salt-inducible kinase 2; salt-inducible protein kinase 2; salt-inducible serine/threonine kinase 2; serine/threonine-protein kinase SIK2; Serine/threonine-protein kinase SNF1-like kinase 2; Sik2; SIK-2; SNF1-like kinase 2; SNF1LK2
Common Name SIK2
Gene Symbol SIK2
KinaseFamily CAMKL Kinase Family
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag GST-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Kinase Group Ser⁄Thr Kinases: CAMK Group
Shipping Condition Dry Ice
Expression System Insect cells
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Full Length
Form Liquid
Protein Subtype Serine/Threonine Kinases
Research Category Signal Transduction
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