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Tocris Bioscience™ SKF 89976A hydrochloride

Product Code. 18064812
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18064812 10 mg 10mg
18044502 50 mg 50mg
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Product Code. 18064812 Supplier Tocris Bioscience™ Supplier No. 1081/10

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Potent GAT-1 inhibitor; brain penetrant

A potent GABA uptake inhibitor, selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). Able to pass the blood-brain barrier after systemic administration and is active in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 85375-15-1
Molecular Formula C22H26ClNO2

Specifications

Quantity 10 mg
Formula Weight 371.91
Purity >99%
Molecular Weight (g/mol) 371.905
Chemical Name or Material SKF 89976A hydrochloride
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