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  5. Tocris Bioscience™ SIS17

Tocris Bioscience™ SIS17
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Product Code. 18064262
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18064262 50 mg 50mg
18044702 10 mg 10mg
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Product Code. 18064262 Supplier Tocris Bioscience™ Supplier No. 7969/50

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Description

Selective HDAC11 inhibitor

SIS17 is a selective HDAC11 inhibitor (IC50 = 0.83 μM). Inhibits demyristoylation of serine hydroxymethyl transferase 2 with no detectable activity at other HDAC subtypes. Combination with Oxaliplatin (Cat. No. 2623) increases cytotoxicity to K562 cells; improves survival of Oxaliplatin-treated 769P cells. Cell permeable.
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Specifications

Chemical Name or Material N'-Hexadecylthiophene-2-carbohydrazide
CAS 2374313-54-7
Quantity 50 mg
Target HDAC11
Molecular Formula C21H38N2OS
Purity 0.95
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