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Scutellarin, MedChemExpress

Product Code. 16453896
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Product Code. 16453896 Supplier Medchem Express Supplier No. HYN0751

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Description

MedChemExpress Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC50s of 26 μM, 253 μM and 136 μM, respectively.

Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC50s of 26 μM, 253 μM and 136 μM, respectively.

Specifications

Chemical Name or Material Scutellarin
CAS 27740-01-8
Color Light Green
Purity Grade Notes Research
Molecular Formula C21H18O12
Quantity 25 mg
Solubility Information DMSO : 100 mg/mL (216.28 mM; Need ultrasonic)
SMILES O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3C(O)=O)=C4O)C2=C4O
Molecular Weight (g/mol) 462.36
Formula Weight 462.36
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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