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Tocris Bioscience™ SB 332235
Potent CXCR2 antagonist
Brand: Tocris Bioscience™ 5671/10
This item is not returnable.
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Description
SB 332235 is a potent CXCR2 antagonist (IC50 = 7.7 nM). Exhibits 285-fold selectivity for CXCR2 over CXCR1. Reduces leukocyte numbers in synovial fluid in acute and chronic rabbit arthritis models. Also reduces synovial fluid eicosanoid and cytokine levels in a rabbit chronic arthritis model. Inhibits proliferation of AML cell lines in vitro.Specifications
| 6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide | |
| 276702-15-9 | |
| 10 mg |
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