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  5. Tocris Bioscience™ SB 332235

Tocris Bioscience™ SB 332235

Product Code. 18786139
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50 mg
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18786139 10 mg 10mg
18770278 50 mg 50mg
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Product Code. 18786139 Supplier Tocris Bioscience™ Supplier No. 5671/10

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Description

Potent CXCR2 antagonist

SB 332235 is a potent CXCR2 antagonist (IC50 = 7.7 nM). Exhibits 285-fold selectivity for CXCR2 over CXCR1. Reduces leukocyte numbers in synovial fluid in acute and chronic rabbit arthritis models. Also reduces synovial fluid eicosanoid and cytokine levels in a rabbit chronic arthritis model. Inhibits proliferation of AML cell lines in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 6-Chloro-3-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-2-hydroxybenzenesulfonamide
CAS 276702-15-9
Quantity 10 mg
Target Chemokine Receptor Antagonists
Molecular Formula C13H10Cl3N3O4S
Formula Weight 410.66
Purity >98%
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