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Invitrogen™ RORA Polyclonal Antibody
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Product Code. 15392381
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50 μg
Unit Size:
50µg
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15392381 50 μg 50µg
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Product Code. 15392381 Supplier Invitrogen™ Supplier No. PA534158

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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Pig (100%).

RORA is a receptor for retinoic acid belonging to the NR1 subfamily of nuclear hormone receptors with a nuclear receptor DNA binding domain. RORA binds either as a monomer or as a homodimer to the retinoic acid response element and thus regulates gene expression and also controls cell function. Though the exact function of RORA is yet unknown, it interacts with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, NM23-1, the product of a tumor metastasis suppressor candidate gene, CDK7, NCOA3 and NCOA6 coactivators. It is found to express in mesenchymal stem cells derived from bone marrow and are known to act by direct modulation of a bone matrix component. It is widely expressed in most of the tissues. Chromosomal aberrations involving RORA may be a cause of acute promyelocytic leukemia (APL).
TRUSTED_SUSTAINABILITY

Specifications

Antigen RORA
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene RORA
Gene Accession No. P35398, P51448
Gene Alias 9530021D13Rik; nmf267; NR1F1; Nuclear receptor ROR-alpha; nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR related orphan receptor A; RAR-related orphan receptor A; RAR-related orphan receptor alpha; retinoic acid receptor-related orphan receptor alpha; retinoid-related orphan receptor alpha; retinoid-related orphan receptor-alpha; ROR Alpha; ROR1; ROR2; ROR3; Rora; Roralpha; ROR-alpha; RORalpha1; RZRA; RZR-ALPHA; sg; staggerer; thyroid hormone nuclear receptor alpha variant 4; tmgc26; transcription factor RZR-alpha
Gene Symbols RORA
Host Species Rabbit
Immunogen Synthetic 20 amino acid peptide from hinge domain of human ROR Alpha.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100147460, 100156637, 100357159, 100759952, 19883, 300807, 478328, 535597, 6095
Target Species Human, Mouse, Rat, Canine, Rabbit, Monkey, Bovine, Hamster, Pig, Horse, Bat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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