missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ RKI 1447 dihydrochloride

Tocris Bioscience™ RKI 1447 dihydrochloride
GREENER_CHOICE

Product Code. 18751789
Change view
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
18751789 50 mg 50mg
18770929 10 mg 10mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 18751789 Supplier Tocris Bioscience™ Supplier No. undefined

Please to purchase this item. Need a web account? Register with us today!

935.00 EUR valid until 2026-03-31
BEST PRICE on Promo! Use promo code "27931" to get your promotional price.
This item is not returnable. View return policy

Description

Potent and selective ROCK inhibitor; antitumor

RKI 1447 dihydrochloride is a potent and selective ROCK inhibitor (IC50 values are 6.2 and 14.5 nM for ROCK2 and ROCK1 respectively); suppresses phosphorylation of ROCK substrates MLC-2 and MYPT-1 in human cancer cells, but has no effect on the phosphorylation levels of Akt, MEK, and S6 kinase. Displays anti-invasive and antitumor activities in breast cancer cells.
TRUSTED_SUSTAINABILITY

Specifications

CAS 1782109-09-4
Quantity 50 mg
Product Type RKI 1447 dihydrochloride
Purity >99%
Molecular Weight (g/mol) 399.29
Inhibitors RKI 1447 dihydrochloride

For Research Use Only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.