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  6. 15792011

Invitrogen™ RGL1 Polyclonal Antibody
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Product Code. 15792011 Shop All Thermo Scientific Products
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100 μL
Unit Size:
100µL
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15792011 100 μL 100µL
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Product Code. 15792011 Supplier Invitrogen™ Supplier No. PA554081

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PHFPCLQKLL DYLTRMMPGS DPERRAQNLL EQFQKQEVET DNGLPNTISF SLEEEEELEG GESAEFTCFS EDLVAEQLTY MDAQLFKKVV PHHCLGCIWS RRD Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 87%.

Ral GDS (Ral guanine nucleotide dissociation stimulator) is a guanine nucleotide exchange factor (GEF) that activates Ral and is implicated in oncogenic Ras-induced cell transformation. RGL1 (ral guanine nucleotide dissociation stimulator-like 1), also known as RGL or RalGDS-like 1, is a 768 amino acid protein that is a putative GEF. Strongly expressed in brain, heart, spleen, kidney and testis, RGL1 is a downstream effector protein that is involved in Ras and Ral signaling pathways. RGL1 contains an N-terminal Ras-GEF domain and a C-terminal Ras-interacting domain that interacts with the GTP-bound form of Ras through its effector loop. Due to its similarity to Ral GDS, RGL1 may be implicated in carcinogenesis. Two isoforms exist due to alternative splicing events.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RGL1
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RGL1
Gene Accession No. Q9NZL6
Gene Alias KIAA0959; mKIAA0959; ral guanine nucleotide dissociation stimulator like 1; ral guanine nucleotide dissociation stimulator,-like 1; ral guanine nucleotide dissociation stimulator-like 1; RalGDS-like 1; RGL; Rgl1
Gene Symbols RGL1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RGL1. Recombinant protein control fragment (Product #RP-92439).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23179
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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